Publications

Running towards amblyopia recovery
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Gabriele Sansevero, ClaudiaTorelli, Rafaele Mazziotti, Alan Consorti, Tommaso Pizzorusso, Nicoletta Berardi and Alessandro Sale

Traumatic Brain Injury Preserves Firing Rates But Disrupts Laminar Oscillatory Coupling and Neuronal Entrainment in Hippocampal CA1
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Paul F. Koch, Carlo Cottone, Christopher D. Adam, Alexandra V. Ulyanova, Robin J. Russo, Maura T. Weber, John D. Arena, Victoria E. Johnson and John A. Wolf

Optogenetic “low‐theta” pacing of the septohippocampal circuit is sufficient for spatial goal finding and is influenced by behavioral state and cognitive demand
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Philippe R. Mouchati, Michelle L. Kloc, Gregory L. Holmes, Sheryl L. White and Jeremy M. Barry

Disrupted Place Cell Remapping and Impaired Grid Cells in a Knockin Model of Alzheimer's Disease
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Heechul Jun, Allen Bramian, Shogo Soma, Takashi Saito, Takaomi C. Saido, and Kei M. Igarashi

Orbitofrontal Cortex Encodes Preference for Alcohol
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John S. Hernandez and David E. Moorman

Regulation of autism-relevant behaviors by cerebellar–prefrontal cortical circuits
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Elyza Kelly, Fantao Meng, Hirofumi Fujita, Felipe Morgado, Yasaman Kazemi, Laura C. Rice, Chongyu Ren, Christine Ochoa Escamilla, Jennifer M. Gibson, Sanaz Sajadi, Robert J. Pendry, Tommy Tan, Jacob Ellegood, M. Albert Basson et al.

Orexin A induced increases in rat locus coeruleus neuronal activity are attenuated by systemic administration of OX1R and OX2R antagonists
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Christopher M. Holton, Gary Gilmour, Keith A. Wafford

Haploinsufficiency of Cyfip2 Causes Lithium‐Responsive Prefrontal Dysfunction
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Seung‐Hyun Lee, Yinhua Zhang, Jina Park, Bowon Kim, Yangsik Kim, Sang Hoon Lee, Gyu Hyun Kim, Yang Hoon Huh, Bokyoung Lee, Yoonhee Kim ... et al.

μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve
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Alexander Dieter, Eric Klein, Daniel Keppeler, Lukasz Jablonski, Tamas Harczos, Gerhard Hoch, Vladan Rankovic, Oliver Paul, Marcus Jeschke, Patrick Ruther, Tobias Moser

Prefrontal - subthalamic pathway supports action selection in a spatial working memory task
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Carla Heikenfeld, Sara Mederos, Changwan Chen, Tatiana Korotkova, Alfons Schnitzler & Alexey Ponomarenko

Multicenter intracranial EEG dataset for classification of graphoelements and artifactual signals
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Petr Nejedly, Vaclav Kremen, Vladimir Sladky, Jan Cimbalnik, Petr Klimes, Filip Plesinger, Filip Mivalt, Vojtech Travnicek, Ivo Viscor, Martin Pail, Josef Halamek, Benjamin H. Brinkmann, Milan Brazdil, Pavel Jurak & Gregory Worrell

GABAergic interneurons excite neonatal hippocampus in vivo
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Yasunobu Murata & Matthew T. Colonnese

Behavior- and Modality-General Representation of Confidence in Orbitofrontal Cortex
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Paul Masset, Torben Ott, Armin Lak, Junya Hirokawa, Adam Kepecs

Impaired Hippocampal-Cortical Interactions during Sleep in a Mouse Model of Alzheimer’s Disease
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Sarah D. Benthem, Ivan Skelin, Shawn C. Moseley, Alina C. Stimmell, Jessica R. Dixon, Andreza S. Melilli, Leonardo Molina, Bruce L. McNaughton, Aaron A. Wilber

Focal Dorsal Hippocampal Nav1.1 Knock Down Alters Place Cell Temporal Coordination and Spatial Behavior
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Sophie Sakkaki, Sylvain Barrière, Alex C Bender, Rod C Scott, Pierre-Pascal Lenck-Santini

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques
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Xin Gong, Diego Mendoza-Halliday, Jonathan T. Ting, Tobias Kaiser, Xuyun Sun, André M. Bastos, Ralf D. Wimmer, Baolin Guo, Qian Chen, Yang Zhou, Maxwell Pruner, Carolyn W.-H. Wu, Demian Park, Karl Deisseroth, Boaz Barak, Edward S. Boyden et al.

Developmental loss of MeCP2 from VIP interneurons impairs cortical function and behavior
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James M Mossner, Renata Batista-Brito, Rima Pant, Jessica A Cardin

Four core properties of the human brain valuation system demonstrated in intracranial signals
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Alizée Lopez-Persem, Julien Bastin, Mathilde Petton, Raphaëlle Abitbol, Katia Lehongre, Claude Adam, Vincent Navarro, Sylvain Rheims, Philippe Kahane, Philippe Domenech & Mathias Pessiglione

Ictal onset sites and γ‐aminobutyric acidergic neuron loss in epileptic pilocarpine‐treated rats
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Megan Wyeth, Monica Nagendran, Paul S. Buckmaster

Memory reactivation in rat medial prefrontal cortex occurs in a subtype of cortical UP state during slow-wave sleep
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Masami Tatsuno, Soroush Malek, LeAnna Kalvi, Adrian Ponce-Alvarez, Karim Ali, David R. Euston, Sonja Grün and Bruce L. McNaughton

Delayed Alternation Task for the Study of Spatial Working and Long Term Memory in Rats
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Megi Hoxha and Marta Sabariego

Cell assemblies in the cortico-hippocampal-reuniens network during slow oscillations
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David Angulo-Garcia, Maëva Ferraris, Antoine Ghestem, Lauriane Nallet-Khosrofian, Christophe Bernard and Pascale P. Quilichini

Gamma activity accelerates during prefrontal development
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Sebastian H. Bitzenhofer, Jastyn A. Pöpplau & Ileana L. Hanganu-Opatz

The relation between neuronal firing, local field potentials and hemodynamic activity in the human amygdala in response to aversive dynamic visual stimuli
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Tommaso Fedele, Athina Tzovara, Bettina Steiger, Peter Hilfiker, Thomas Grunwald, Lennart Stieglitz, Hennric Jokeit, Johannes Sarnthein

Dysregulation of external globus pallidus‐subthalamic nucleus network dynamics in parkinsonian mice during cortical slow‐wave activity and activation
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Jaclyn Essig, Joshua B. Hunt, and Gidon Felsen

Electrocorticography reveals spatiotemporal neuronal activation patterns of verbal fluency in patients with epilepsy

Shawniqua Williams Roberson, Preya Shah, Vitória Piai, Heather Gatens, Abba M. Krieger, Timothy H. Lucas II, Brian Litt

Directional deep brain stimulation leads reveal spatially distinct oscillatory activity in the globus pallidus internus of Parkinson's disease patients
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Joshua E. Aman, Luke A. Johnson, David Escobar Sanabria, Jing Wang, Remi Patriat, Meghan Hill, Ethan Marshall, Colum D. MacKinnon, Scott E. Cooper, Lauren E. Schrock, Michael C. Park, Noam Harel, Jerrold L. Vitek

Enhanced cortical responsiveness during natural sleep in freely behaving mice
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Sumire Matsumoto, Kaoru Ohyama, Javier Díaz, Masashi Yanagisawa, Robert W. Greene & Kaspar E. Vogt

Harnessing ‘Time’ To Enhance Memory: Using Closed-Loop Technology To Facilitate Oscillatory Synchrony & Support Cognition
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Andrew C. Garcia

Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson’s Disease
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Jun Young Heo, Min-Ho Nam, Hyung Ho Yoon, Jeongyeon Kim, Yu Jin Hwang, Woojin Won, Dong Ho Woo, Ji Ae Lee, Hyun-Jung Park, Seonmi Jo, Min Joung Lee, Sunpil Kim, Jeong-Eun Shim, Dong-Pyo Jang, Kyoung I. Kim, Sue H. Huh, C. Justin Lee, et al.

Hippocampal Ripple Coordinates Retrosplenial Inhibitory Neurons during Slow-Wave Sleep
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Ashley N.Opalka, Wen-qiang Huang, Jun Liu, Hualou Liang, Dong V. Wang

Differences in task-phase-dependent time-frequency patterns of local field potentials in the dorsal and ventral regions of the monkey lateral prefrontal cortex
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Kazuhiro Sakamoto, Norihiko Kawaguchi, Hajime Mushiake

A neural basis of probabilistic computation in visual cortex
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Edgar Y. Walker, R. James Cotton, Wei Ji Ma & Andreas S. Tolias

IL-17a promotes sociability in mouse models of neurodevelopmental disorders
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Michael Douglas Reed, Yeong Shin Yim, Ralf D. Wimmer, Hyunju Kim, Changhyeon Ryu, Gwyneth Margaret Welch, Matias Andina, Hunter Oren King, Ari Waisman, Michael M. Halassa, Jun R. Huh & Gloria B. Choi

Distinct directional couplings between slow and fast gamma power to the phase of theta oscillations in the rat hippocampus
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Haiteng Jiang, Ali Bahramisharif, Marcel A. J. van Gerven, Ole Jensen

Somatostatin interneurons in the prefrontal cortex control affective state discrimination in mice
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Diego Scheggia, Francesca Managò, Federica Maltese, Stefania Bruni, Marco Nigro, Daniel Dautan, Patrick Latuske, Gabriella Contarini, Marta Gomez-Gonzalo, Linda Maria Requie, Valentina Ferretti, Giulia Castellani, Daniele Mauro, Papaleo et al.

Abnormal locus coeruleus activity during sleep alters sleep signatures of memory consolidation and impairs place cell stability and spatial memory
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Swift, K., Gross, B., Frazer, M., Bauer, D., Clark, K., Vazey, E., AstonJones, G., Li, Y., Pickering, A. E., Sara, S., & Poe, G.

Extent of Single-Neuron Activity Modulation by Hippocampal Interictal Discharges Predicts Declarative Memory Disruption in Humans
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Chrystal M. Reed, Clayton P. Mosher, Nand Chandravadia, Jeffrey M. Chung, Adam N. Mamelak and Ueli Rutishauser

Optogenetic gamma stimulation rescues memory impairments in an Alzheimer’s disease mouse model
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Guillaume Etter, Suzanne van der Veldt, Frédéric Manseau, Iman Zarrinkoub, Emilie Trillaud-Doppia & Sylvain Williams

Economic Decisions through Circuit Inhibition
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Sébastien Ballesta, Camillo Padoa-Schioppa

Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment
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Mattia Chini, Jastyn A. Pöpplau, Christoph Lindemann, Sebastian H. Bitzenhofer, Christoph Mulert, Ileana L. Hanganu-Opatz

Dynamically changing neuronal activity supporting working memory for predictable and unpredictable durations
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Jong Chan Park, Jung Won Bae, Jieun Kim, Min Whan Jung

Longitudinal Functional Assessment of Brain Injury Induced by High-Intensity Ultrasound Pulse Sequences
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Meijun Ye, Krystyna Solarana, Harmain Rafi, Shyama Patel, Marjan Nabili, Yunbo Liu, Stanley Huang, Jonathan A. N. Fisher, Victor Krauthamer, Matthew Myers & Cristin Welle

Dentate gyrus mossy cells share a role in pattern separation with dentate granule cells and proximal CA3 pyramidal cells
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Douglas GoodSmith, Heekyung Lee, Joshua P. Neunuebel, Hongjun Song and James J. Knierim

Locus Coeruleus Optogenetic Stimulation and the Estrous Cycle Manipulate Sleep Characteristics and Memory Consolidation
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Kevin M. Swift

A rat model for assessing the long-term safety and performance of peripheral nerve electrode arrays
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Benjamin Shafera, Cristin Welle, Srikanth Vasudevan

Behavioral and Cortical Correlates of Self-Suppression, Anticipation, and Ambivalence in Rat Tickling
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Shimpei Ishiyama, Lena V. Kaufmann, Michael Brecht

Multifunctional multi-shank neural probe for investigating and modulating long-range neural circuits in vivo
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Hyogeun Shin, Yoojin Son, Uikyu Chae, Jeongyeon Kim, Nakwon Choi, Hyunjoo J. Lee, Jiwan Woo, Yakdol Cho, Soo Hyun Yang, C. Justin Lee & Il-Joo Cho

Defined neuronal populations drive fatal phenotype in a mouse model of Leigh Syndrome
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Irene Bolea, Alejandro Gella, Elisenda Sanz, Patricia Prada-Dacasa, Fabien Menardy, Angela Michelle Bard, Pablo Machuca-Márquez, Abel Eraso-Pichot, Guillem Mòdol Caballero, Xavier Navarro, Franck Kalume, Albert Quintana

Projection from the Amygdala to the Thalamic Reticular Nucleus Amplifies Cortical Sound Responses
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Mark Aizenberg, Solymar Rolón-Martínez, Tuan Pham, Winnie Rao, Julie S. Haas, Maria N. Geffen

The effect of sevoflurane and isoflurane anesthesia on single unit and local field potentials
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Daniil P. Aksenov, Michael J. Miller, Conor J. Dixon, Alice M. Wyrwicz

Egocentric boundary vector tuning of the retrosplenial cortex
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Andrew S. Alexander, Lucas C. Carstensen, James R. Hinman, Florian Raudies, G. William Chapman, Michael E. Hasselmo

Altered Hippocampal–Prefrontal Dynamics Following Medial Prefrontal Stroke in Mouse
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Kristin L. Hillman, Hannah J. Wall, Luke O. Matthews, Emma K. Gowing & Andrew N. Clarkson

Neuronal Responses to Conspecifics in the Ventral CA1
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Rajnish P. Rao, Moritz von Heimendahl, Viktor Bahr, Michael Brecht

Monosynaptic Hippocampal-Prefrontal Projections Contribute to Spatial Memory Consolidation in Mice
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Sonja Binder, Matthias Mölle, Michael Lippert, Ralf Bruder, Sonat Aksamaz, Frank Ohl, J. Simon Wiegert and Lisa Marshall

Neuronal representation of environmental boundaries in egocentric coordinates
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James R. Hinman, G. William Chapman & Michael E. Hasselmo

Developmental dysfunction of prefrontal–hippocampal networks in mouse models of mental illness
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Victoria C. Oberlander, Xiaxia Xu, Mattia Chini, Ileana L. Hanganu‐Opatz

Place cell assemblies remain intact, despite reduced phase precession, after cholinergic disruption
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Sarah Jo C. Venditto, Brianna Le, Ehren L Newman

Emotional Mirror Neurons in the Rat’s Anterior Cingulate Cortex
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Maria Carrillo, Yinging Han, Filippo Migliorati, Ming Liu, Valeria Gazzola, Christian Keysers

Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors
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Jacquelyn Nestor, Yoshiyuki Arinuma, Tomás S. Huerta, Czeslawa Kowal, Elham Nasiri, Nina Kello, Yuichiro Fujieda, Alison Bialas, Tim Hammond, Uma Sriram, Beth Stevens, Patricio T. Huerta, Bruce T. Volpe, Betty Diamond

Near physiological spectral selectivity of cochlear optogenetics
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Alexander Dieter, Carlos J. Duque-Afonso, Vladan Rankovic, Marcus Jeschke, and Tobias Moser

Parallel Processing of Sound Dynamics across Mouse Auditory Cortex via Spatially Patterned Thalamic Inputs and Distinct Areal Intracortical Circuits
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Ji Liu, Matthew R. Whiteway, Alireza Sheikhattar, Daniel A. Butts, Behtash Babadi, Patrick O. Kanold

Post-learning Hippocampal Replay Selectively Reinforces Spatial Memory for Highly Rewarded Locations

Frédéric Michon, Jyh-Jang Sun, Chae Young Kim, Davide Ciliberti, Fabian Kloosterman

The dorsolateral striatum regulates habits by way of performance vigor when actions are initiated
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Adam C.G. Crego, Fabián Štoček, Alec G. Marchuk, James E. Carmichael, Matthijs A.A. van der Meer, and Kyle S. Smith

Functional Architecture of the Rat Parasubiculum
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Researchers at the Berstein Center investigated parasubicular circuits of the rat by anatomical analysis combined with juxtacellular recording/labeling and tetrode recordings during spatial exploration. Anterograde tracing experiments showed that parasubicular neurons extend long “circumcurrent” axons establishing a “global” internal connectivity. The parasubiculum is a prime target of GABAergic and cholinergic medial septal inputs. Other input structures include the subiculum, presubiculum, and anterior thalamus. Functional analysis of identified and unidentified parasubicular neurons shows strong theta rhythmicity of spiking, a large fraction of head-direction selectivity (50%, 34 of 68), and spatial responses (grid, border and irregular spatial cells, 57%, 39 of 68). Parasubicular output preferentially targets patches of calbindin-positive pyramidal neurons in layer 2 of medial entorhinal cortex, which might be relevant for grid cell function. These findings suggest the parasubiculum might shape entorhinal theta rhythmicity and the (dorsoventral) integration of information across grid scales.

Qiusong Tang, Andrea Burgalossi, Christian Laut Ebbesen, Juan Ignacio Sanguinetti-Scheck, Helene Schmidt, John J. Tukker, Robert Naumann, Saikat Ray, Patricia Preston-Ferrer, Dietmar Schmitz, and Michael Brecht

Gamma oscillations coordinate food seeking
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Scientists at the Leibniz-Institut für Molekulare Pharmakologie (FMP) and NeuroCure Cluster of Excellence in Berlin discovered a neuronal circuit which regulates the hypothalamus and activates food-seeking in mice. Surprisingly, this neural mechanism appeared to utilize gamma oscillations, and does not depend on hunger. Optogenetics helped to shed light on the behavioral function of this circuit. The findings allow for better understanding of the mechanisms of feeding behavior, and could lead to development of innovative therapies to treat eating disorders.

Rüdiger Land, Peter Baumhoff, Jochen Tillein, Stephen G. Lomber, Peter Hubka and Andrej Kral

Open Access Cross-Modal Plasticity in Higher-Order Auditory Cortex of Congenitally Deaf Cats Does Not Limit Auditory Responsiveness to Cochlear Implants
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Rüdiger Land, Peter Baumhoff, Jochen Tillein, Stephen G. Lomber, Peter Hubka and Andrej Kral

Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks
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Using the Digital Lynx SX in conjunction with Neuronexus optotrodes and Omicron Laser, they established a protocol that combines optogenetics with electrophysiological recordings from neonatal mice in vivo to elucidate the substrate of early network oscillations in the prefrontal cortex.

Sebastian H Bitzenhofer, Joachim Ahlbeck, Amy Wolff, J. Simon Wiegert, Christine E. Gee, Thomas G. Oertner & Ileana L. Hanganu-Opatz

Coupled Oscillations Mediate Directed Interactions between Prefrontal Cortex and Hippocampus of the Neonatal Rat
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Marco D. Brockmann, Beatrice Po schel, Nicole Cichon, and Ileana L. Hanganu-Opatz

Oscillatory Entrainment of Primary Somatosensory Cortex Encodes Visual Control of Tactile Processing
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Kay Sieben, Brigitte Roder, and Ileana L. Hanganu-Opatz

Optical control of hippocampal GABAergic neurons
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Bender AC & Lenck-Santini PP

Hierarchical computation in the canonical auditory cortical circuit
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Craig A. Atencioa, Tatyana O. Sharpeeb, and Christoph E. Schreinera

Receptive field dimensionality increases from the auditory midbrain to cortex
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Craig A. Atencio, Tatyana O. Sharpee, and Christoph E. Schreiner

Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
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Craig A. Atencio*, Christoph E. Schreiner

Inhibition of Protein Kinase M Disrupts the Stable Spatial Discharge of Hippocampal Place Cells in a Familiar Environment
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Jeremy M. Barry, Bruno Rivard, Steven E. Fox, Andre A. Fenton, Todd C. Sacktor, and Robert U. Muller

Chronic multi-electrode neural recording in free-roaming monkeys
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Steven J. Eliades*, XiaoqinWang

Corticostriatal neurons in auditory cortex drive decisions during auditory discrimination
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Petr Znamenskiy & Anthony M. Zador

The dorsomedial striatum encodes net expected return, critical for energizing performance vigor
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Alice Y Wang, Keiji Miura & Naoshige Uchida

Construction of Microdrive Arrays for Chronic Neural Recordings in Awake Behaving Mice
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Eric H. Chang, Stephen A. Frattini, Sergio Robbiati, Patricio T. Huerta