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The NanoZ was specifically designed for multichannel electrode arrays. It features very low test currents for measuring electrode site impedances and electrode impedance spectroscopy (EIS). Several inbuilt electroplating modes are provided for automated site impedance matching, site activation, and cleaning.

A virtual digital multimeter (DMM) displays impedance measurements or the realtime plating voltage, depending on the mode of operation. If R||C is checked, the resistive and capacitive components of the current impedance measurement will be displayed, assuming a parallel RC equivalent circuit model.
ADPT-NZ-EIB36 (Omnetics)

The NanoZ comes supplied with a NZA-DIP16 adaptor for probes that use a DIP16 connector, and a variety of other adaptors are available for commonly used interconnects such as those from Omnetics and Millmax.  Neuralynx provides adaptors for connecting the NanoZ to any HS18 or HS16 series of electrode interface product (EIB's).  Also, adaptors are available for NeuroNexus Probes (C16, MR16, C32, MR32 and F Probes).  Please contact with any questions.

Intuitive GUI

User-programmable electrode site configurations provide a meaningful way to visualize the integrity of the electrode array, and allow subsets of channels to be tested and/or conditioned by selecting the relevant sites with a few mouse clicks.

NanoZ Setup

With this setup, it is not necessary to have a height-adjustable laboratory jack.  Instead, you can raise or lower the NanoZ to immerse the probe in the solution. 

The NanoZ application supports arbitrary probe site configurations and, once defined in ʻelectrodes.iniʼ, handles the channel mapping transparently.  Several example probes are provided with the default installation. Probe definitions can be modified and new definitions can be added; refer to Appendix C (in the NanoZ User Manual) for a detailed description on how to do this.

32 Channel Impedance Results in < 1min

Impedance Test Mode
This mode rapidly cycles through all (or a subset) of the channels on the selected probe, measuring the impedance of each electrode.  The impedance results are tabulated in the Report Window.  Options for impedance testing include:  setting a test frequency, choosing the number of cycles and setting a delay. 

DC Electroplate Mode
This mode cycles through all (or a subset) of the electrodes on the selected probe, applying a controlled DC constant current to each site.  It has two sub-modes of operation:  fixed plating time per channel; and match impedances mode. 

  • Plating with gold for nichrome OR Pt Black with Pt/Ir wire
  • Deposition of conductive polymers to lower site impedance and improve the site charge capacity
  • Electrode site cleaning
  • In vivo or in vitro rejuvenation of electrode sites
  • Tissue lesioning and electrode track marking
Impedance Spectroscopy Mode
This mode cycles through all (or a subset) of electrodes on the selected probe, measuring the impedance of each electrode at multiple test frequencies. 

Activitation Mode
This mode uses cyclic voltammetry to increase the charge capacity of all electrodes on the selected probe for either a fixed duration, or to match a target electrode charge capacity.  Activation mode applies a bipolar, constant current square-wave to the electrode, which both lowers the impedance and increases the charge capacity, two properties that are desirable for effective electrical stimulation.

General Troubleshooting
The NanoZ is susceptible to EMI because it uses very small test signals for measuring impedance.  To ensure accurate results, periodically check the signal quality using the Scope display of the NanoZ application.  The NanoZ software will report if any part of the test signal is clipped, and highlight in yellow the affected channels in the Report window.  If necessary, enclosure the setup in wire mest or aluminum foil to shield it from EMI, and be sure to connect the shield to the reference wire. 

Upcoming Events


Japanese Neuroscience Society
Yokohama Japan
September 14th-17th, 2011

SFN (Society For Neuroscience)
Washington, DC
November 12th-16th, 2011

Neuralynx Booth #325

AES (American Epilepsy Society)
Baltimore, MD
December 2nd-6th, 2011
Neuralynx Booth #110

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